Chicken Alfredo Lasagna Roll-Ups

If you’re craving a cozy, comforting meal that combines the rich creaminess of Alfredo sauce with tender chicken and melty cheese, then you’re in for a treat with these Chicken Alfredo Lasagna Roll-Ups. This dish takes classic lasagna to a whole new level by rolling up each noodle with a luscious filling, making every bite ooze with flavor and texture. Perfect for weeknight dinners or special occasions, these roll-ups are easy to assemble, bake, and serve, giving you that satisfying Italian-inspired meal without the fuss of layered lasagna.

Why Chicken Alfredo Lasagna Roll-Ups is Worth Your Time

Chicken Alfredo Lasagna Roll-Ups bring together the best elements of creamy Alfredo sauce, wholesome chicken, and cheeses like ricotta, mozzarella, and Parmesan in a way that’s both visually stunning and incredibly tasty. Unlike traditional lasagna, these roll-ups portion out perfectly, making serving a breeze and reducing mess on the plate. The combination of garlic, onion, and basil seasoning adds depth to the filling, while fresh parsley garnish brightens the dish with a pop of color and flavor.

Beyond their deliciousness, these roll-ups are flexible for busy cooks looking for a make-ahead option. They can be prepped in advance and baked just before mealtime, ideal for hosting guests or meal prepping for the week. Plus, the ingredients are pantry and fridge staples, so you don’t need to make a special trip to the store.

Ingredient Checklist

• 9 lasagna noodles
• 2 cups cooked, shredded chicken (rotisserie or homemade)
• 2 cups ricotta cheese
• 2 cups shredded mozzarella cheese
• 1 cup grated Parmesan cheese
• 2 cups Alfredo sauce (store-bought or homemade)
• 1 teaspoon garlic powder
• 1 teaspoon onion powder
• 1 teaspoon dried basil
• 1 teaspoon salt
• 1/2 teaspoon black pepper
• 1/2 cup chopped fresh parsley (for garnish)

Equipment & Tools

• Large pot – for boiling lasagna noodles
• Colander – to drain noodles
• Mixing bowl – to combine chicken and cheese mixture
• Measuring cups and spoons – for precise seasoning
• Baking dish (9×13 inch) – to bake the roll-ups
• Spatula or spoon – for spreading the filling and sauce
• Aluminum foil – to cover the dish while baking

Method: Chicken Alfredo Lasagna Roll-Ups

Step 1: Prepare the Lasagna Noodles

Fill a large pot with water, add a pinch of salt, and bring it to a boil. Add the 9 lasagna noodles and cook according to the package instructions until al dente, usually around 8-10 minutes. Stir occasionally to prevent sticking. Drain the noodles in a colander and rinse them briefly with cold water to stop cooking. Lay the noodles flat on a clean kitchen towel or parchment paper to dry and cool.

Step 2: Make the Filling

In a large mixing bowl, combine the 2 cups of cooked, shredded chicken with ricotta cheese, 1 cup shredded mozzarella, ½ cup grated Parmesan, garlic powder, onion powder, dried basil, salt, and black pepper. Mix gently until all ingredients are well incorporated. This creamy, flavorful filling is the heart of your Chicken Alfredo Lasagna Roll-Ups.

Step 3: Assemble the Roll-Ups

Preheat your oven to 375°F (190°C). Spread about ½ cup of Alfredo sauce evenly on the bottom of your baking dish. Take one lasagna noodle and spread a generous layer of the chicken and cheese filling evenly over the surface. Sprinkle a bit of shredded mozzarella on top for extra cheesiness. Roll the noodle up tightly from one end to the other and place it seam side down in the baking dish. Repeat with the remaining noodles and filling.

Step 4: Top and Bake

Once all roll-ups are arranged in the dish, pour the remaining Alfredo sauce evenly over them. Sprinkle the remaining mozzarella and Parmesan cheese over the top. Cover the dish with aluminum foil and bake for 25 minutes. Remove the foil and bake for an additional 10-15 minutes until the cheese is bubbly and golden.

Step 5: Garnish and Serve

Remove from the oven and let the roll-ups rest for 5 minutes. Sprinkle chopped fresh parsley over the top for a fresh, vibrant finish. Serve warm and enjoy the creamy, cheesy goodness of your Chicken Alfredo Lasagna Roll-Ups.

Ingredient Swaps & Substitutions

• Chicken: Use leftover turkey or rotisserie chicken for convenience.
• Ricotta Cheese: Substitute with cottage cheese for a lighter option, blending it smooth before using.
• Mozzarella: Use part-skim mozzarella for less fat or provolone for a different flavor profile.
• Alfredo Sauce: Try making your own sauce with butter, cream, and Parmesan, or swap for a creamy béchamel sauce.
• Herbs: Fresh basil can be used instead of dried basil for a brighter herbal note.
• Lasagna Noodles: Use no-boil noodles if short on time, just add a few extra minutes to baking.

Flavor Logic

This recipe thrives on the harmony between creamy, cheesy, and savory flavors. The ricotta and mozzarella cheeses create a luscious filling that contrasts with the tender, shredded chicken, while Parmesan adds a sharp, nutty edge. Garlic and onion powders provide aromatic depth without overpowering the dish, and dried basil ties the flavors together with a subtle herbaceous note. The Alfredo sauce envelopes the roll-ups with its silky texture, making each bite indulgently smooth. Finally, the fresh parsley garnish adds a hint of freshness and color, balancing the rich flavors beautifully.

Storing, Freezing & Reheating

Leftover Chicken Alfredo Lasagna Roll-Ups store well in an airtight container in the refrigerator for up to 3 days. To reheat, cover with foil and warm in a 350°F oven for about 15-20 minutes until heated through. For freezing, assemble the roll-ups but do not bake. Place the baking dish tightly covered with plastic wrap and aluminum foil in the freezer for up to 3 months. When ready to enjoy, thaw overnight in the refrigerator, then bake as directed, adding an extra 10 minutes if needed to ensure they are warmed through.

Chicken Alfredo Lasagna Roll-Ups FAQs

Can I make Chicken Alfredo Lasagna Roll-Ups ahead of time?

Absolutely! These roll-ups are perfect for meal prep or entertaining. Assemble them a day ahead and keep covered in the refrigerator. When you’re ready, just bake them fresh for a hot, delicious meal.

Can I use a different type of cheese?

Yes, you can substitute cheeses according to your preference. For example, swapping mozzarella with provolone or adding a bit of fontina can add different flavor dimensions, but stick to cheeses that melt well for the best texture.

Is it possible to make this recipe vegetarian?

Definitely. Simply omit the chicken and increase the cheese filling or add sautéed vegetables like spinach or mushrooms for extra flavor and texture. You might also want to use a vegetarian-friendly Alfredo sauce.

What can I serve with Chicken Alfredo Lasagna Roll-Ups?

This dish pairs beautifully with a crisp green salad or roasted vegetables. For a complementary pasta side, check out this Creamy Roasted Cauliflower Alfredo Ziti recipe, which shares similar flavors and will round out your meal nicely.

You Might Also Like

• Baked Four Cheese Lasagna Roll Ups – A cheesy twist on the classic roll-up.
• Creamy Roasted Cauliflower Alfredo Ziti – A comforting pasta with roasted veggies and Alfredo sauce.

Save & Share

If you love this recipe for Chicken Alfredo Lasagna Roll-Ups, be sure to save it to your favorite recipe collection and share it with friends and family. It’s a crowd-pleaser that’s sure to become a staple in your dinner rotation!

Enjoy this delightful, creamy, and cheesy Chicken Alfredo Lasagna Roll-Ups recipe that’s simple to make yet impressive to serve. Each bite is a celebration of comfort food done right, perfect for any night of the week or a special meal with loved ones. Happy cooking!

Share on Pinterest