Creamy Cajun Chicken Penne

If you’re craving a dish that’s bursting with flavor, rich in texture, and perfect for any weeknight dinner, look no further than this Creamy Cajun Chicken Penne. It’s a beautiful marriage of tender chicken, smoky Cajun spices, and a luscious creamy sauce that clings to perfectly cooked penne pasta. This recipe is straightforward, satisfying, and will quickly become a staple in your kitchen repertoire.

Why It’s My Go-To

There’s something incredibly comforting about a creamy pasta dish, and when you add that kick of Cajun seasoning, it takes it to a whole new level. This Creamy Cajun Chicken Penne hits all the right notes — it’s spicy yet smooth, hearty but not heavy, and full of vibrant colors and textures. It’s one of those recipes that feels fancy enough for guests but comes together quickly enough for a busy night. Plus, the balance of protein, veggies, and carbs makes it a full meal in one bowl. I love how adaptable it is, too; whether you’re cooking for family or meal prepping for the week, it never disappoints.

Ingredient Rundown

• 8 ounces penne pasta – The perfect noodle to soak up that creamy sauce without getting mushy.
• 1 pound chicken breast, diced – Lean, tender, and takes on the Cajun spices beautifully.
• 2 tablespoons olive oil – For sautéing and adding richness.
• 1 medium onion, chopped – Adds sweetness and depth to the sauce.
• 2 cloves garlic, minced – Essential for that aromatic base.
• 1 teaspoon Cajun seasoning – The heart and soul of this dish, bringing smoky heat.
• 1/2 teaspoon smoked paprika – Enhances smokiness and color.
• 1/2 teaspoon black pepper – Adds a subtle sharpness.
• 1 cup heavy cream – Creates that silky, rich sauce.
• 1 cup chicken broth – Keeps the sauce flavorful and light.
• 1 cup bell pepper, sliced – Adds sweetness and a pop of color.
• 1/2 cup grated Parmesan cheese – Gives the sauce a nutty, savory finish.
• Salt to taste – Balances all the flavors.
• Fresh parsley, chopped (for garnish) – A fresh, vibrant touch to finish.

Gear Up: What to Grab

• Large pot – For boiling the penne pasta.
• Large skillet or sauté pan – To cook the chicken and build the sauce.
• Wooden spoon or spatula – For stirring everything together.
• Sharp knife and cutting board – To dice the chicken and chop veggies.
• Measuring cups and spoons – For precise seasoning and liquids.
• Colander – To drain the pasta perfectly.

Creamy Cajun Chicken Penne: How It’s Done

Step 1: Cook the Penne Pasta

Bring a large pot of salted water to a boil. Add the penne pasta and cook according to package instructions until al dente, usually about 10-12 minutes. Drain the pasta and set aside, reserving a little pasta water for later.

Step 2: Sauté the Chicken

Heat the olive oil in a large skillet over medium-high heat. Add the diced chicken breast, seasoning it with half of the Cajun seasoning and a pinch of salt. Cook until the chicken is golden and cooked through, about 5-7 minutes. Remove the chicken from the skillet and set it aside.

Step 3: Build the Flavor Base

In the same skillet, add a little more olive oil if needed. Toss in the chopped onion and sauté until translucent, about 3-4 minutes. Add the minced garlic and cook for another 30 seconds until fragrant. Stir in the remaining Cajun seasoning, smoked paprika, and black pepper to toast the spices slightly.

Step 4: Make the Creamy Sauce

Pour in the chicken broth and heavy cream, stirring to combine. Bring the mixture to a gentle simmer and let it thicken slightly, about 5 minutes. Add the sliced bell peppers and cook until they soften but still retain some crunch, around 3 minutes.

Step 5: Combine and Finish

Return the cooked chicken to the skillet and stir everything together. Add the drained penne pasta and gently toss to coat in the creamy sauce. Sprinkle in the grated Parmesan cheese and stir until melted and incorporated. If the sauce feels too thick, add a splash of reserved pasta water to loosen it up.

Step 6: Garnish and Serve

Taste and adjust salt and pepper if needed. Serve hot, garnished with fresh chopped parsley for a bright finish. This dish pairs wonderfully with a simple green salad or crusty bread to soak up every last bit of sauce.

Holiday & Seasonal Touches

• Add roasted cherry tomatoes in summer for a burst of sweetness.
• Swap bell peppers for sautéed mushrooms during autumn for earthier flavors.
• Mix in fresh spinach or kale at the end for a nutrient boost all year round.
• Top with crumbled crispy bacon for a festive touch (if desired).

Slip-Ups to Skip

• Don’t overcook the chicken — it should be just cooked through to stay juicy.
• Avoid using pre-shredded Parmesan with additives; freshly grated cheese melts better.
• Be careful with the Cajun seasoning — start with less and add more to taste to avoid overwhelming the dish.
• Don’t skip reserving pasta water; it helps adjust the sauce consistency perfectly.

Save for Later: Storage Tips

This Creamy Cajun Chicken Penne keeps beautifully in an airtight container in the fridge for up to 3 days. When reheating, add a splash of broth or cream to restore the sauce’s creaminess and heat gently on the stove or microwave. It’s also freezer-friendly for up to one month — just thaw overnight in the fridge before reheating.

Helpful Q&A

Can I use a different pasta shape?

Absolutely! While penne is ideal for holding the sauce, you can easily swap in rigatoni, fusilli, or even spaghetti. For a twist, try the Creamy Cajun Chicken Rigatoni recipe for a similar flavor profile with a different noodle shape.

How spicy is the Cajun seasoning in this recipe?

The heat level is moderate, designed to add warmth and flavor without overpowering. You can adjust the amount of Cajun seasoning or substitute with a milder blend if you prefer less spice.

What can I use instead of heavy cream?

If you want a lighter option, full-fat coconut milk or evaporated milk can work, but the sauce won’t be quite as rich. For a dairy-free version, try a cashew cream or a plant-based cooking cream, keeping in mind it may slightly alter the flavor.

Can I make this dish in one pot?

Yes! For a quicker cleanup, check out this One Pot Cajun Chicken Alfredo which uses similar flavors but cooks everything together in one pan for convenience.

Because You Liked This

• Creamy Cajun Chicken Fettuccine – A delightful variation using fettuccine noodles for a silky, wide noodle experience.
• One Pot Cajun Chicken Alfredo – Perfect for busy nights when you want robust flavor with minimal cleanup.
• Creamy Cajun Chicken Rigatoni – A hearty, textured pasta that holds the creamy sauce beautifully.

Ready to Cook?

This Creamy Cajun Chicken Penne recipe is a fantastic way to bring a little spice and comfort to your dinner table. With simple ingredients and straightforward steps, you can whip up a dish that feels indulgent without the fuss. Whether you’re cooking for yourself, family, or friends, this pasta will impress with its creamy texture, bold Cajun flavors, and satisfying bite. So grab your skillet and pot, and let’s get cooking! Your taste buds will thank you.

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