Preheat the oven to 300°F (150°C). Line two baking sheets with foil and lightly spray them with non-stick olive oil spray; set aside.
In a large bowl, whisk together 1 cup plain Greek yogurt, 1 teaspoon garlic powder, 1/2 teaspoon paprika, 1/2 teaspoon Italian seasoning, 1 teaspoon salt, and 1/2 teaspoon black pepper until smooth.
Stir in the juice of 1/2 lemon (about 1/2 lemon) and add the chicken tenders, tossing to coat each piece evenly in the yogurt marinade. Refrigerate while you prepare the breading.
In a shallow dish, combine 1 1/2 cups panko, 1/3 cup grated Parmesan, 1 1/2 teaspoons garlic powder, 1/2–3/4 teaspoon chili powder, 1 1/2 teaspoons salt, and 1/2 teaspoon black pepper; whisk to combine.
One at a time, remove a tender from the marinade and press it into the panko mixture to coat both sides, shaking off excess. Place coated tenders on the prepared baking sheets in a single layer.
Lightly spray the tops of the coated tenders with olive oil spray. Bake for about 20 minutes at 300°F until cooked through and the coating is set.
If you want extra crispiness, broil the tenders for about 1 minute per side, watching closely to avoid burning.