Make the buffalo marinade: In a medium mixing bowl whisk together 1/4 cup hot sauce, 2 tablespoons honey, 1 tablespoon lime juice, 1 teaspoon garlic powder, 1 teaspoon chili powder, 1 teaspoon salt, 1/2 teaspoon ground cumin, 1/2 teaspoon smoked paprika, 1/2 teaspoon onion powder, and 1/4 teaspoon black pepper.
Reserve 1/4 cup of the marinade in a separate container for the glaze; refrigerate it until needed.
In a shallow dish or freezer bag combine the remaining marinade with 2 tablespoons olive oil. Add the pounded chicken breasts and toss to coat evenly. Refrigerate and marinate for at least 2 hours or up to overnight.
Prepare the glaze: Whisk the reserved marinade with 1 tablespoon honey and 1 1/2 teaspoons lime juice, then chill until ready to use.
Stovetop method: If time allows, let chicken sit at room temperature 15–30 minutes. Heat a large nonstick skillet over medium-high until very hot. Add the chicken and cook undisturbed 3–5 minutes until well browned on the first side.
Flip the chicken, cover the skillet, reduce heat to medium, and cook 5–7 more minutes (depending on thickness) until cooked through. Remove to a cutting board and let rest 5 minutes before slicing.
Grill method: Preheat and grease the grill to medium (375–450°F). Let chicken sit at room temperature 15–30 minutes. Grill undisturbed 5–7 minutes per side until cooked through and an instant-read thermometer registers 160°F. Remove and rest 5 minutes before slicing.
Brush the sliced or whole rested chicken with the prepared glaze to taste; use more for spicier results and less for milder heat.