Preheat your oven to 400°F (200°C). This high temperature will help the tenders crisp up beautifully.
In a mixing bowl, combine the mayonnaise, egg, flour, paprika, and ranch seasoning. Mix until smooth. Add the chicken tenders to the bowl, ensuring they are well-coated.
In another bowl, melt the 2 tablespoons of unsalted butter and add the panko breadcrumbs. Stir until the breadcrumbs are fully coated in the butter.
Take each coated chicken tender and dip it into the panko mixture, pressing gently to ensure an even coating. Place the tenders on a baking sheet lined with parchment paper.
Spray the tops of the tenders lightly with cooking spray. Bake in the preheated oven for 20-25 minutes, or until golden brown and cooked through (internal temperature should reach 165°F).
While the chicken is baking, mix the melted butter, hot sauce, light brown sugar, and garlic powder in a bowl. Adjust the heat level by adding more or less hot sauce according to your preference.
Once the chicken tenders are done baking, remove them from the oven and toss them in the buffalo sauce until well coated.
Serve your buffalo chicken tenders hot, accompanied by ranch or blue cheese dressing for dipping. Enjoy the crispy, spicy goodness!