Bring a large pot of salted water to a boil. Add 8 oz pasta of choice and cook according to package instructions until al dente. Drain the pasta and set aside, reserving about ½ cup of the pasta water.
While the pasta is cooking, heat 2 tablespoons olive oil in a large skillet over medium-high heat. Add the diced chicken breast and season with 1 teaspoon garlic powder, 1 teaspoon onion powder, 1 teaspoon smoked paprika, salt, and pepper. Sauté the chicken until golden and cooked through, about 6-8 minutes. Remove the chicken from the skillet and set aside.
In the same skillet, reduce heat to medium. Add 1 teaspoon minced chipotle pepper in adobo sauce and sauté for about 1 minute until fragrant. Pour in 1 cup chicken broth and 1 cup heavy cream. Stir well to combine, scraping any browned bits from the bottom of the pan. Let the sauce simmer gently for 3-5 minutes until it thickens slightly.
Reduce heat to low and add 1 cup grated Parmesan cheese, stirring continuously until cheese melts into a smooth, creamy sauce. Return cooked chicken to the skillet and mix evenly into the sauce.
Add the drained pasta to the skillet with the creamy chipotle chicken sauce. Toss gently to coat the pasta in the sauce. If sauce is too thick, add a splash of reserved pasta water to reach desired consistency.
Remove skillet from heat and sprinkle 2 tablespoons fresh chopped cilantro over the top. Serve immediately for best flavor and texture.