Preheat the oven to 450°F (232°C). Line a large rimmed baking sheet with foil and place an oven-safe cooling rack on top; spray the rack with nonstick spray.
Pat the chicken wings very dry with paper towels, removing as much moisture as possible.
In a large bowl, whisk together baking powder, seasoned salt, garlic powder, black pepper, and cayenne pepper until evenly combined.
Add the wings to the bowl and toss (or shake in a zip-top bag) until each piece is evenly coated with the dry mixture.
Arrange the coated wings in a single layer on the prepared rack, leaving space between pieces so air can circulate.
Bake for 30 minutes, then flip each wing and bake an additional 30–40 minutes until the wings are deep golden and very crispy.
While the wings finish baking, whisk together the melted butter and Buffalo sauce in a large bowl.
When wings are done, transfer them to the bowl with the sauce and toss quickly to coat, then serve immediately.