Preheat the oven to 375°F (190°C).
In a shallow bowl, whisk together the all-purpose flour, kosher salt, and freshly ground black pepper.
Pat the chicken dry and dredge each piece in the flour mixture, shaking off excess.
In a separate bowl, whisk the honey, orange juice, rice vinegar, soy sauce, cornstarch, sesame oil, minced garlic, minced ginger, and crushed red pepper flakes (if using) until smooth. Set aside.
Heat the vegetable oil in a large oven-safe skillet over medium heat until shimmering.
Add the chicken to the hot skillet and sear until golden brown on both sides, 3–4 minutes per side; work in batches if needed to avoid overcrowding.
Pour the prepared honey sauce over the seared chicken, turning the pieces to coat them evenly in the sauce.
Transfer the skillet to the preheated oven and bake for 10–12 minutes, or until the chicken reaches 165°F (74°C) and is cooked through.
Remove from the oven, spoon any sauce over the chicken, and sprinkle with chopped green onion and sesame seeds before serving.