Preheat the oven to 400°F (200°C).
In a shallow bowl or pie plate, combine the salt, garlic powder, onion powder, crushed red pepper flakes, black pepper, and lemon zest; mix with a fork until the dry seasonings are evenly moistened by the zest.
Add the panko to the seasoned lemon mixture and stir with a fork until evenly combined; set aside.
Place the chicken breast on a cutting board, cover with plastic wrap, and pound to an even thickness (about 3/4-inch) using a meat mallet or rolling pin.
Pat the chicken dry with paper towels, then rub both sides with 1 teaspoon olive oil.
Press both sides of the oiled chicken into the panko mixture so the crumbs adhere and the chicken is well coated; set aside.
Heat 1 tablespoon olive oil in a cast iron (or ovenproof) skillet over medium-high heat until shimmering.
Fry the chicken 4 minutes per side, or until the panko is golden brown.
Transfer the skillet to the preheated oven and bake until the chicken reaches 165°F (74°C) internal temperature, about 4–6 minutes more depending on thickness.
Remove the chicken to a plate and let rest 3 minutes, then sprinkle with lemon juice to taste and serve.