Preheat the oven to 350°F and spray a 9x13-inch baking dish with nonstick cooking spray.
Cook the lasagna noodles according to package directions, drain, and set aside.
In a large skillet over medium heat, cook the ground beef and Italian sausage until no longer pink; drain any excess fat.
Add Stone House Seasoning, dried basil, dried oregano, pasta sauce, and tomato paste to the skillet; stir and simmer until the sauce thickens, about 5–10 minutes.
In a large bowl, lightly beat the egg, then add softened cream cheese, Greek yogurt, 2 cups shredded mozzarella, 1/4 cup shredded Parmesan, and chopped parsley if using; stir until smooth and combined.
Spoon 1 cup of the meat sauce into the prepared baking dish and spread into an even layer.
Arrange a layer of cooked lasagna noodles over the sauce, then spread one-third of the cheese mixture over the noodles and top with 1 cup of meat sauce. Repeat this noodle, cheese, and sauce layering two more times.
Top with a final layer of lasagna noodles and the remaining meat sauce, then cover the dish loosely with aluminum foil.
Bake covered for 40 minutes.
Remove the foil and sprinkle the remaining 2 cups shredded mozzarella and 1/4 cup shredded Parmesan over the top; bake uncovered until the cheese is browned, about 15 minutes.
Let the lasagna rest for 10 minutes before cutting and serving.