Cheesy Chicken Alfredo Casserole

If you’re craving a comforting, creamy, and cheesy meal that’s as satisfying as it is simple, this Cheesy Chicken Alfredo Casserole is your new go-to. Imagine tender chicken and perfectly cooked pasta tossed in a luscious Alfredo sauce, layered with gooey mozzarella and Parmesan cheese, then baked to golden bubbly perfection. It’s a one-dish wonder that brings the flavors of a classic Italian favorite right to your dinner table with minimal fuss and maximum flavor. Whether you’re feeding a family or meal prepping for the week ahead, this casserole hits all the right notes.

Why Cooks Rave About It

This Cheesy Chicken Alfredo Casserole is beloved for several reasons. First, it’s incredibly versatile — you can easily swap out the pasta or vegetables to suit your pantry or preferences. The creamy Alfredo sauce is rich without being overpowering, striking a perfect balance with the tender shredded chicken. Plus, the blend of mozzarella and Parmesan cheese creates that irresistible melty, golden crust that’s hard to beat. It’s also a fantastic way to use leftover chicken, transforming it into a hearty, crowd-pleasing meal. Best of all? It’s quick to assemble yet feels like a special occasion dish.

Ingredient Checklist

• 2 cups cooked pasta (penne or rotini work best for holding the sauce)
• 2 cups cooked, shredded chicken (rotisserie chicken is a great shortcut)
• 2 cups Alfredo sauce (store-bought or homemade, your choice)
• 1 cup shredded mozzarella cheese (for that melty, stringy texture)
• 1 cup grated Parmesan cheese (adds a sharp, nutty flavor)
• 1/2 cup cooked broccoli florets (adds color and nutrition)
• 1/2 teaspoon garlic powder (for subtle depth of flavor)
• 1/2 teaspoon onion powder (to enhance savory notes)
• Salt and pepper to taste
• 1/2 teaspoon Italian seasoning (herbaceous warmth)
• 1/4 cup chopped fresh parsley (for garnish and freshness)

Toolbox for This Recipe

• Baking dish (9×9-inch or similar size works perfectly)
• Large mixing bowl (for combining all ingredients)
• Measuring cups and spoons (accuracy matters!)
• Wooden spoon or spatula (for gentle folding)
• Oven mitts (safety first!)
• Knife and cutting board (for chopping parsley and prepping broccoli)

Cheesy Chicken Alfredo Casserole: From Prep to Plate

Step 1: Preheat and Prepare

Start by preheating your oven to 350°F (175°C). While it warms, gather all your ingredients. If your broccoli isn’t cooked yet, steam or blanch the florets until tender but still vibrant green.

Step 2: Mix the Base

In a large mixing bowl, combine the cooked pasta and shredded chicken. Pour in the Alfredo sauce, garlic powder, onion powder, Italian seasoning, salt, and pepper. Stir gently until everything is evenly coated.

Step 3: Add Veggies and Cheese

Fold the cooked broccoli florets into the mixture, then stir in half of the mozzarella and Parmesan cheese. This layering inside ensures cheesy goodness throughout the casserole.

Step 4: Transfer to Baking Dish

Spoon the mixture into your prepared baking dish and spread it out evenly. Sprinkle the remaining mozzarella and Parmesan cheese over the top to create that irresistible golden crust.

Step 5: Bake to Perfection

Bake uncovered for 25-30 minutes or until the cheese on top is melted, bubbly, and starting to turn golden brown. Keep an eye on it in the last few minutes to prevent over-browning.

Step 6: Garnish and Serve

Remove the casserole from the oven and let it rest for 5 minutes. Sprinkle the chopped fresh parsley on top for a pop of color and fresh flavor. Serve warm and enjoy!

Seasonal Ingredient Swaps

• Swap broccoli with steamed asparagus or green beans in spring or summer.
• Use roasted butternut squash or sweet potato cubes for a fall twist.
• Try adding sautéed mushrooms or bell peppers for extra umami and color.
• Replace cooked chicken with turkey or even a vegetarian protein like chickpeas for variation.

Chef’s Rationale

Every element in this Cheesy Chicken Alfredo Casserole is thoughtfully chosen to create a harmonious dish:

• The pasta shape—penne or rotini—holds onto the creamy sauce beautifully, ensuring every bite is flavorful.
• Shredded chicken provides tender protein that’s easy to distribute throughout the casserole.
• The combination of mozzarella and Parmesan balances meltiness with sharpness, offering layers of cheesy texture and taste.
• Broccoli adds a nutritious crunch and a burst of color, breaking up the richness.
• Seasonings like garlic powder, onion powder, and Italian seasoning deepen the flavor without overpowering the creamy Alfredo base.

Keep-It-Fresh Plan

This casserole keeps beautifully in the refrigerator for up to 3 days when stored in an airtight container. To reheat, cover with foil and warm in a 350°F oven until heated through, or microwave in short bursts, stirring occasionally. For longer storage, freeze portions in freezer-safe containers for up to 2 months. Thaw overnight in the fridge before reheating.

Common Qs About Cheesy Chicken Alfredo Casserole

Can I use fresh Alfredo sauce instead of store-bought?

Absolutely! Fresh Alfredo sauce made from butter, cream, garlic, and Parmesan will elevate the casserole with fresher flavors. Just ensure it’s thick enough to coat the pasta without making the dish watery.

What type of chicken works best for this recipe?

Cooked, shredded chicken breast or thigh meat both work wonderfully here. Rotisserie chicken is a convenient, flavorful shortcut that saves time.

Is it okay to substitute the broccoli with other vegetables?

Yes! Feel free to swap broccoli with vegetables like spinach, zucchini, or peas, depending on your preference or seasonal availability.

How can I make this casserole more protein-packed?

Adding an extra cup of shredded chicken or mixing in cooked bacon or pancetta can boost the protein content. Just keep an eye on seasoning adjustments to balance flavors.

Try These Next

• Baked Three Cheese Chicken Penne – Another cheesy pasta bake with a delightful cheese blend.
• Cheesy Baked Buffalo Chicken Pasta – For those who love a little spice with their creamy chicken dishes.

Let’s Eat

Gather your loved ones, dish out generous portions of this Cheesy Chicken Alfredo Casserole, and watch as it quickly disappears from the plate. Its creamy sauce, tender chicken, and melted cheese make every forkful pure comfort food bliss. Pair it with a simple green salad or garlic bread for a wholesome, satisfying meal that’s perfect any night of the week.

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