The Best Beef & Cheeseburger Pasta Casserole

If you’re craving a hearty, comforting meal that combines all the flavors of a classic cheeseburger with the ease of a pasta casserole, look no further. The Best Beef & Cheeseburger Pasta Casserole brings together tender penne pasta, savory ground beef, rich cheeses, and a flavorful tomato base for a dish that’s sure to become a family favorite. It’s a one-dish wonder that’s simple enough for a weeknight dinner yet satisfying enough for weekend gatherings. Let’s dive into why this recipe stands out and how you can master it in your own kitchen.

Why This Recipe Is Reliable

This casserole recipe is a winner for multiple reasons. First, it uses pantry staples and straightforward ingredients that are easy to find and budget-friendly. The combination of penne pasta and ground beef creates a filling base, while the tomato sauce and diced tomatoes add just the right amount of tang and moisture. The blend of cheddar and mozzarella cheese melts perfectly, giving the casserole a creamy, cheesy texture that’s reminiscent of a cheeseburger without the bun.

The seasoning is simple but effective — Italian seasoning, garlic, salt, and pepper enhance the flavors without overpowering them, making this dish approachable for all tastes. Plus, the addition of sour cream and beef broth adds a subtle richness and depth that elevates the sauce to something truly special.

Lastly, this recipe is incredibly forgiving. Whether you slightly overcook the pasta or adjust the seasoning to your liking, it still turns out delicious every time. This consistency makes The Best Beef & Cheeseburger Pasta Casserole a trusted go-to meal.

Your Shopping Guide

• 12 oz penne pasta: Look for high-quality pasta with a good bite—semolina-based pasta works best to hold up well in the casserole.
• 1 lb ground beef: Choose lean ground beef with about 85% lean meat to keep the dish flavorful without being greasy.
• 1 medium onion, chopped: Yellow or white onions add a sweet savoriness when sautéed.
• 2 cloves garlic, minced: Fresh garlic enhances the aroma and depth of flavor.
• 1 can (15 oz) tomato sauce: Opt for a smooth tomato sauce without added herbs so you can control the seasoning.
• 1 can (14.5 oz) diced tomatoes, undrained: Choose diced tomatoes with no added seasoning to keep the flavors balanced.
• 2 cups shredded cheddar cheese: Sharp or mild cheddar works—choose based on your preference.
• 1 cup shredded mozzarella cheese: Use whole milk mozzarella for better melting.
• 2 tsp Italian seasoning: A blend of dried oregano, basil, thyme, and rosemary adds an herby kick.
• 1 tsp salt and 1/2 tsp black pepper: Essential for seasoning every component.
• 1/4 cup sour cream: Adds creaminess and a slight tang—look for full-fat for best results.
• 1/4 cup beef broth: Enhances the meatiness of the sauce—choose a low-sodium version to better control saltiness.

Recommended Tools

• Large pot: For boiling the penne pasta to al dente.
• Large skillet or sauté pan: To brown the ground beef and sauté the onions and garlic.
• Measuring cups and spoons: For precise ingredient quantities.
• Colander: To drain the cooked pasta.
• 9×13 inch casserole dish: Perfect size for layering and baking the casserole evenly.
• Mixing spoon or spatula: To combine ingredients thoroughly.
• Cheese grater: If shredding your own cheddar or mozzarella cheese.

How to Prepare The Best Beef & Cheeseburger Pasta Casserole

Step 1: Cook the Pasta

Bring a large pot of salted water to a boil. Add 12 oz of penne pasta and cook according to package instructions until al dente, usually about 10-11 minutes. Drain the pasta and set aside.

Step 2: Brown the Ground Beef

In a large skillet over medium-high heat, add 1 lb of ground beef. Break it up with a spoon and cook until browned and no longer pink, about 6-8 minutes. Drain excess fat if necessary.

Step 3: Sauté Onion and Garlic

Add 1 chopped medium onion and 2 cloves minced garlic to the skillet with the beef. Cook until the onion is translucent and fragrant, about 3-4 minutes.

Step 4: Add Tomatoes and Seasoning

Pour in 1 can (15 oz) tomato sauce and 1 can (14.5 oz) diced tomatoes with their juice. Stir in 2 teaspoons Italian seasoning, 1 teaspoon salt, and 1/2 teaspoon black pepper. Add 1/4 cup beef broth and stir everything together. Let the sauce simmer for 5-7 minutes to marry the flavors.

Step 5: Combine Pasta and Sauce

Turn off the heat and stir in 1/4 cup sour cream until fully incorporated. Add the cooked penne pasta into the skillet and mix gently to coat the pasta evenly with the sauce.

Step 6: Assemble the Casserole

Preheat your oven to 350°F (175°C). Transfer the beef and pasta mixture to a greased 9×13 inch casserole dish. Sprinkle 2 cups shredded cheddar cheese and 1 cup shredded mozzarella cheese evenly over the top.

Step 7: Bake

Bake in the preheated oven for 20-25 minutes, or until the cheese is bubbly and golden brown around the edges. Remove from the oven and let it sit for 5 minutes before serving.

Make It Year-Round

• Switch up the cheese: Try adding pepper jack for a spicy twist or gouda for a smoky flavor.
• Add vegetables: Toss in diced bell peppers, mushrooms, or spinach while sautéing for extra nutrition.
• Use different pasta shapes: Fusilli or rigatoni work well if penne isn’t available.
• Make it creamy: Stir in a dollop of cream cheese or ricotta just before baking for an ultra-lush texture.
• Serve with fresh herbs: Garnish with chopped parsley or basil to brighten the dish.

Behind-the-Scenes Notes

This recipe was inspired by the classic cheeseburger flavor profile but designed to be a one-pan meal that’s quick to prepare and easy to customize. The secret to The Best Beef & Cheeseburger Pasta Casserole’s rich taste lies in balancing the acidity of the tomatoes with the creaminess of the sour cream and cheese. The beef broth adds a meaty depth without overwhelming the other ingredients.

For an extra touch of indulgence, consider serving alongside Garlic Butter Steak And Mushroom Fettuccine on a special occasion or pairing with a simple green salad for a lighter option.

Storing, Freezing & Reheating

This casserole stores beautifully in the refrigerator for up to 3 days. To store, cover the dish tightly with plastic wrap or transfer leftovers to an airtight container.

• Freezing: You can freeze the casserole before baking. Cover tightly with foil and freeze for up to 2 months. Thaw overnight in the refrigerator before baking as directed.
• Reheating: Reheat individual portions in the microwave or warm the entire dish in the oven at 350°F (175°C) until heated through, about 15-20 minutes.

Frequently Asked Questions

Can I use ground turkey or chicken instead of beef?

Yes! Ground turkey or chicken are great lean alternatives that work well in this casserole. Just brown the meat thoroughly and adjust the seasoning to taste.

Is it necessary to drain the fat from the cooked beef?

Draining excess fat helps prevent the casserole from becoming greasy, especially if you use higher-fat ground beef. For leaner beef, draining is optional.

Can I prepare this casserole ahead of time?

Absolutely. You can assemble the casserole the night before, cover it, and refrigerate. When ready, bake it directly from the fridge—just add a few extra minutes to the baking time.

What can I serve with this dish?

This casserole pairs wonderfully with a crisp green salad or steamed vegetables. For a more indulgent meal, try it alongside Baked Three Cheese Chicken Penne for a cheese-lover’s feast.

More Recipes You’ll Love

• Garlic Butter Steak And Mushroom Fettuccine – A rich and comforting pasta perfect for steak lovers.
• Baked Three Cheese Chicken Penne – Creamy, cheesy, and packed full of tender chicken and pasta.

Ready to Cook?

Gather your ingredients and tools, and get ready to create The Best Beef & Cheeseburger Pasta Casserole that will satisfy your cravings and warm your soul. The flavors meld beautifully in this cheesy, meaty, pasta-packed dish, making it a true crowd-pleaser. Whether you’re feeding your family or hosting friends, this casserole is sure to impress.

With simple steps and straightforward ingredients, you’ll be amazed at how easy it is to bring this hearty, delicious meal to your table. So preheat your oven, boil the penne, and prepare to enjoy a casserole that’s as comforting as a cheeseburger but with all the convenience of pasta. Happy cooking!

Share on Pinterest